For almost the entire 20th century, health science—the science that dictates what we eat, what supplements we take, and what treatments we receive—was built by looking at only one type of body: the male body.

The women were not in the clinical trials.

Not by chance, but by design.

A science written in the masculine

In the 1960s and 1970s, when many of the doses and protocols we follow today were defined, researchers decided to exclude women from the studies "to avoid hormonal complexity."

It sounds absurd, but it was literal: the menstrual cycle was considered a bothersome variable .

The result:

• The reference doses (RDA) were based on male bodies.

• The drugs and nutrients were tested on healthy young men.

• Female symptoms were considered “atypical” or “subjective”.

Decades later, we are still dragging along that legacy.

The invisible cost of an incomplete science

That gap is not just historical: it directly affects how women feel every day .

When a supplement does not take hormonal variations into account, it may not work — or even worsen certain symptoms.

When studies ignore the impact of chronic stress or fragmented sleep on female metabolism, energy and recovery protocols remain incomplete.

The consequence is silent but massive:

unexplained fatigue, hormonal dysregulation, recurring deficiencies, and a constant feeling of "doing everything right" without results.

It's not your fault.

The thing is, science wasn't on our side .

The new wave of knowledge

In the last decade, research has begun to correct its course.

Today we know, with real data, that:

• Cortisol, iron, and magnesium levels fluctuate significantly throughout the menstrual cycle.

• The inflammatory response and insulin sensitivity are different in women.

• The impact of stress on the thyroid and mitochondria is more pronounced in the female body.

And most importantly: when studies are designed specifically for women, the results change radically.

Personalized nutrition based on cycle phases, sleep, energy, or mental load is no longer a trend: it's science.

What SANA represents

SANA was created to change this situation.

As a scientific response to a void that should never have existed.

Not to sell supplements, but to give women back a science that includes them .

We design formulas where every ingredient, dose, and study is based on female biology.

We do not extrapolate results based on men.

We translate evidence into real well-being.
Taking care of yourself isn't a fad. It's knowledge.

We want taking care of yourself to stop being a confusing or guilt-ridden routine.

Let every decision about your health be guided by information, not noise.

Because when you understand your body, you make better choices .

And when science is on your side, you feel different .

References

1. Zucker I, Beery AK. “Males still dominate animal studies.” Nature , 2010.

2. Regitz-Zagrosek V, et al. “Sex and gender differences in pharmacology.” Nat Rev Drug Discov , 2020.

3. Mauvais-Jarvis F. “Sex differences in metabolic homeostasis.” Diabetes , 2015.

4. Clayton JA, Collins FS. “Policy: NIH to balance sex in cell and animal studies.” Nature , 2014.

🧩 This article is part of “Science for Women”, SANA's space where we translate scientific evidence into practical knowledge applicable to women's health.